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Article

Persons with age-related maculopathy risk genotypes and clinically normal eyes have reduced mesopic vision.

Investigative ophthalmology & visual science - 1 Feb 2011

Feigl Beatrix, Cao Dingcai, Morris Charles P, Zele Andrew J

Abstract excerpt

PURPOSE: To determine whether participants with normal visual acuity, no ophthalmoscopically signs of age-related maculopathy (ARM) in both eyes, and who are carriers of the CFH, LOC387715, and HRTA1 high-risk genotypes (gene-positive) have impaired rod- and cone-mediated mesopic visual function compared with persons who do not carry the risk genotypes (gene-negative). METHODS: Fifty-three Caucasian study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20881291
DOI: 10.1167/iovs.10-5967
PMCID: PMC3053098

Genes

CFH
ARMS2
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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