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Article

Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.

American journal of ophthalmology - 1 Dec 2009

Andreoli Michael T, Morrison Margaux A, Kim Ben J, Chen Ling, Adams Scott M, Miller Joan W, DeAngelis Margaret M, Kim Ivana K

Abstract excerpt

PURPOSE: To examine the interaction of genotypic variation of 16 single-nucleotide polymorphisms (SNP) in the complement factor H (CFH) and LOC387715/ARMS2/HTRA1 loci with clinical characteristics of age-related macular degeneration (AMD). DESIGN: Retrospective cohort study. METHODS: Eighty-four patients with neovascular AMD were genotyped using direct sequencing or Sequenom iPLEX technology. The Fisher exact...

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Source

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Identifiers

PMID: 19796758
DOI: 10.1016/j.ajo.2009.07.002
PMCID: PMC2787659

Genes

ARMS2
HTRA1
RPE
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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