Article
Variations in five genes and the severity of age-related macular degeneration: results from the Muenster aging and retina study.
Eye (London, England) - 1 Dec 2009
Farwick A, Dasch B, Weber B H F, Pauleikhoff D, Stoll M, Hense H-W
Abstract excerpt
AIMS: Little is known about the role of genetic variants in the early stages of age-related macular degeneration (AMD). We aimed to investigate how genetic variations within five well-defined genes relate to AMD severity. METHODS: We analysed SNPs in the genes for complement factor H (CFH), age-related maculopathy susceptibility (ARMS2), HtrA serine peptidase 1 (HtrA1), complement factor B (CFB), and complement...
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