Article
Impact of age-related maculopathy susceptibility 2, high-temperature requirement A serine peptidase 1, and complement factor H genetic variants on clinical phenotypes of age-related macular degeneration.
Indian journal of ophthalmology - 1 Feb 2026
Ranga Divya, Kaur Simarpreet, Nallabelli Nayudu, Sharma Surya Prakash, Tigari Basavaraj, Dogra Mohit, Katoch Deeksha, Sharma Suresh K, Singh Ramandeep, Singh Nirbhai
Abstract excerpt
PURPOSE: Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the elderly. This study investigated the association of single-nucleotide polymorphisms (SNPs) in ARMS2, HTRA1, and CFH with AMD and its clinical phenotypes and systemic cytokine profiles in a North Indian population. METHOD: A total of 113 AMD patients and 99 controls were genotyped using TaqMan assays. All patients...
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