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Article

Genetic Associations of Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration.

Investigative ophthalmology & visual science - 1 Jul 2025

Curcio Christine A, Mullins Robert F, Stone Edwin M, Goerdt Lukas, Kar Deepayan, Gao Liyan, McGwin Gerald, Owsley Cynthia

Abstract excerpt

Purpose: To compare genetic associations of rod- and cone-driven vision with those previously defined for delayed rod-mediated dark adaptation (RMDA), a functional risk indicator for incident age-related macular degeneration (AMD). Methods: In adults aged ≥60 years with two normal eyes (per the Age-Related Eye Disease Study 9-step scale) or with AMD in one or both eyes, we measured RMDA at 5° superior retina,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40673740
DOI: 10.1167/iovs.66.9.50
PMCID: PMC12282642

Genes

ARMS2
CFH

Provenance

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