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Article

Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Dec 2010

Yu Xinfeng, Dhakal Ishwori B, Beggs Marjorie, Edavana Vineetha Koroth, Williams Suzanne, Zhang Xuemei, Mercer Kelly, Ning Baitang, Lang Nicholas P, Kadlubar Fred F, Kadlubar Susan

Abstract excerpt

Sulfotransferase isoform 1A1 (SULT1A1) is the most highly expressed hepatic sulfotransferase and is involved in the biotransformation of a wide variety of endo- and xenobiotics. A common single nucleotide polymorphism (SNP) in the coding region of SULT1A1, several proximal promoter SNPs, and copy number variation (CNV) are associated with altered enzymatic activity, but these variants do not fully account for the...

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Identifiers

PMID: 20881232
DOI: 10.1093/toxsci/kfq296
PMCID: PMC2984532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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