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Human SULT1A1 gene: copy number differences and functional implications.

Human molecular genetics - 1 Mar 2007

Hebbring Scott J, Adjei Araba A, Baer Janel L, Jenkins Gregory D, Zhang Jianping, Cunningham Julie M, Schaid Daniel J, Weinshilboum Richard M, Thibodeau Stephen N

Abstract excerpt

SULT1A1, which catalyzes the sulfate conjugation of a wide variety of natural and synthetic compounds, is genetically polymorphic. Biochemical and pharmacogenetic studies have demonstrated that individual variation in the level of enzyme activity is inherited. Common single-nucleotide polymorphisms (SNPs) located in the open reading frame and in the 5'-flanking region (5'-FR) may account for a portion of this...

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PMID: 17189289
DOI: 10.1093/hmg/ddl468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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