Article
Genetic variants in the 8q24 locus and risk of testicular germ cell tumors.
Human genetics - 1 May 2008
Cook Michael B, Graubard Barry I, Quraishi Sabah M, Yeager Meredith, Chanock Stephen J, Crenshaw Andrew, Erickson Ralph L, Rubertone Mark V, Thomas Gilles, McGlynn Katherine A
Abstract excerpt
Much evidence supports the premise that population genetic variation contributes significantly to the risk of testicular germ-cell tumor (TGCT). However, investigations of the association between genomic markers and TGCT susceptibility are scarce. Single nucleotide polymorphisms (SNPs) at the locus 8q24 have recently been found to be associated with prostate, colorectal and breast cancer. The US Servicemen's...
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