Article
So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests.
American journal of human genetics - 1 Dec 2007
Conneely Karen N, Boehnke Michael
Abstract excerpt
Contemporary genetic association studies may test hundreds of thousands of genetic variants for association, often with multiple binary and continuous traits or under more than one model of inheritance. Many of these association tests may be correlated with one another because of linkage disequilibrium between nearby markers and correlation between traits and models. Permutation tests and simulation-based methods...
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