Article
A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms.
Genetic epidemiology - 1 May 2008
Gao Xiaoyi, Starmer Joshua, Martin Eden R
Abstract excerpt
Multiple testing is a challenging issue in genetic association studies using large numbers of single nucleotide polymorphism (SNP) markers, many of which exhibit linkage disequilibrium (LD). Failure to adjust for multiple testing appropriately may produce excessive false positives or overlook true positive signals. The Bonferroni method of adjusting for multiple comparisons is easy to compute, but is well known...
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