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Article

Meta-analysis of genome-wide association studies.

Cold Spring Harbor protocols - 1 Jun 2010

de Bakker Paul I W, Neale Benjamin M, Daly Mark J

Abstract excerpt

Individual genome-wide association studies have only limited power to find novel loci underlying complex traits and common diseases. With relatively modest sample and effect sizes, a true association between genotype and phenotype may never meet genome-wide statistical significance (P < 5 x 10(-8)) in a single study. Through meta-analysis, novel susceptibility loci can be discovered by effectively summing the...

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PMID: 20516189
DOI: 10.1101/pdb.top81

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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