Article
Overview of Statistical Methods for Genome-Wide Association Studies (GWAS).
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Hayes Ben
Abstract excerpt
This chapter provides an overview of statistical methods for genome-wide association studies (GWAS) in animals, plants, and humans. The simplest form of GWAS, a marker-by-marker analysis, is illustrated with a simple example. The problem of selecting a significance threshold that accounts for the large amount of multiple testing that occurs in GWAS is discussed. Population structure causes false positive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
