Article
Loss of chromosome 9p21 and decreased p16 expression correlate with malignant gastrointestinal stromal tumor.
World journal of gastroenterology - 7 Oct 2010
Zhang Yun, Cao Hui, Wang Ming, Zhao Wen-Yi, Shen Zhi-Yong, Shen Dan-Ping, Ni Xing-Zhi, Wu Zhi-Yong, Shen Yan-Ying, Song Yan-Yan
Abstract excerpt
AIM: To investigate loss of heterozygosity (LOH) of chromosome 9p21 and the prognostic relevance of p16 expression in gastrointestinal stromal tumor (GIST). METHODS: Fifty-one GIST patients (30 men and 21 women; median age 59 years; range 29-80 years) treated surgically within a 10-year period were grouped by aggressive behavior risk (17 with very low and low, 14 intermediate, and 20 high risk). GISTs were...
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