Article
Loss of P16 expression and chromosome 9p21 LOH in predicting outcome of patients affected by superficial bladder cancer.
The Journal of surgical research - 1 Dec 2007
Bartoletti Riccardo, Cai Tommaso, Nesi Gabriella, Roberta Girardi Lucia, Baroni Gianna, Dal Canto Maurizio
Abstract excerpt
OBJECTIVES: To evaluate the prognostic role of p16 expression and loss of heterozygosity (LOH) on chromosome 9p21 in patients affected by low-grade (G1-G2) urothelial bladder cancer. METHODS: Fifty-six consecutive patients with diagnosis of urothelial bladder cancer were enrolled in this prospective study. LOH analysis was performed on a blood/tumor pair sample of each patient, by using polymerase chain reaction...
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