Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene variations of nitric oxide synthase regulate the effects of a saturated fat rich meal on endothelial function.

Clinical nutrition (Edinburgh, Scotland) - 1 Apr 2011

Delgado-Lista Javier, Garcia-Rios Antonio, Perez-Martinez Pablo, Fuentes Francisco, Jiménez-Gomez Yolanda, Gomez-Luna Maria Jose, Parnell Laurence D, Marin Carmen, Lai Chao Qiang, Perez-Jimenez Francisco, Ordovas Jose Maria, Lopez-Miranda Jose

Abstract excerpt

BACKGROUND & AIMS: Endothelial nitric oxide synthase (eNOS) gene variations have been linked to a higher risk for cardiovascular diseases (CVD) by unknown mechanisms. Our aim was to determine if two single nucleotide polymorphisms (SNPs) located in NOS3 (E298D and i19342) interfere with microvascular endothelial function (MEF) and/or oxidative stress during the postprandial state. METHODS: MEF was assessed with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, LDL

Share to Endothelium

Share to Fatty Acids

Share to Nitric Oxide Synthase Type III

Share to Oxidative Stress

Share to Postprandial Period

Source

Identifiers

PMID: 20870316
DOI: 10.1016/j.clnu.2010.08.006

Genes

NOS3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene variations of nitric oxide synthase regulate the effects of a saturated fat rich meal on endothelial function.PMID 20870316Read ↗

NOS3 Glu298Asp polymorphism interacts with virgin olive oil phenols to determine the postprandial endothelial function in patients with the metabolic syndrome.Semantic proximity Read ↗

Endothelium-dependent vasodilation in conduit and resistance vessels in relation to the endothelial nitric oxide synthase gene.Semantic proximity Read ↗

Glu298Asp polymorphism influences the beneficial effects of fish oil fatty acids on postprandial vascular function.Semantic proximity Read ↗

Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function.Semantic proximity Read ↗

NOS3 gene polymorphisms are associated with risk markers of cardiovascular disease, and interact with omega-3 polyunsaturated fatty acids.Semantic proximity Read ↗

Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study.Semantic proximity Read ↗

Association Patterns of Endothelial Nitric Oxide Synthase Gene (NOS3) Variant Glu298Asp with Blood Pressure and Serum Lipid Levels in Subjects with Coronary Artery Disease from Pakistan.Semantic proximity Read ↗

Influence of fat intake and BMI on the association of rs1799983 NOS3 polymorphism with blood pressure levels in an Iberian population.Semantic proximity Read ↗

Common genetic variation at the endothelial nitric oxide synthase locus and relations to brachial artery vasodilator function in the community.Semantic proximity Read ↗

Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms.Semantic proximity Read ↗

Endothelial nitric oxide synthase haplotypes are associated with features of metabolic syndrome.Semantic proximity Read ↗

The Glu298Asp single nucleotide polymorphism in the endothelial nitric oxide synthase gene differentially affects the vascular response to acute consumption of fruit and vegetable puree based drinks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.