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Article

Common genetic variation at the endothelial nitric oxide synthase locus and relations to brachial artery vasodilator function in the community.

Circulation - 6 Sept 2005

Kathiresan Sekar, Larson Martin G, Vasan Ramachandran S, Guo Chao-Yu, Vita Joseph A, Mitchell Gary F, Keyes Michelle J, Newton-Cheh Christopher, Musone Stacy L, Lochner Amy L, Drake Jared A, Levy Daniel, O'Donnell Christopher J, Hirschhorn Joel N, Benjamin Emelia J

Abstract excerpt

BACKGROUND: Sequence variants at the endothelial nitric oxide synthase (NOS3) locus have been associated with endothelial function measures, but replication has been limited. METHODS AND RESULTS: In reference pedigrees, we characterized linkage disequilibrium structure at the NOS3 locus using 33 common single nucleotide polymorphisms (SNPs). Eighteen SNPs that capture underlying common variation were genotyped in...

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PMID: 16129794
DOI: 10.1161/CIRCULATIONAHA.105.544619

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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