Article
Endothelial nitric oxide synthase haplotypes are associated with features of metabolic syndrome.
Clinical chemistry - 1 Jan 2007
González-Sánchez José L, Martínez-Larrad María T, Sáez María E, Zabena Carina, Martínez-Calatrava María J, Serrano-Ríos Manuel
Abstract excerpt
BACKGROUND: The metabolic syndrome, a cluster of several metabolic disorders, is increasingly being recognized as a risk factor for cardiovascular disease. Endothelium-derived nitric oxide facilitates skeletal muscle glucose uptake, and data from animal models indicate that endothelial nitric oxide synthase (eNOS) gene-null mice present with a phenotype of insulin resistance, hypertension, and...
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