Article
Glu298Asp polymorphism influences the beneficial effects of fish oil fatty acids on postprandial vascular function.
Journal of lipid research - 1 Oct 2012
Thompson Abby K, Newens Katie J, Jackson Kim G, Wright John, Williams Christine M
Abstract excerpt
Our objective was to determine whether the endothelial nitric oxide synthase (eNOS) Glu298Asp polymorphism influences vascular response to raised NEFA enriched with saturated fatty acids (SFA) or long-chain (LC) n-3 polyunsaturated fatty acids (PUFA). Subjects were prospectively recruited for genotype (Glu298, n = 30 and Asp298, n = 29; balanced for age and gender) consumed SFA on two occasions, with and without...
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