Article
Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Feb 2010
Kingah Pascal L, Luu Hung N, Volcik Kelly A, Morrison Alanna C, Nettleton Jennifer A, Boerwinkle Eric
Abstract excerpt
Endothelial nitric oxide synthase breaks down nitric oxide and has a key role in blood pressure regulation. Earlier studies have shown associations between single nucleotide polymorphisms (SNPs) in the NOS3 gene and hypertension. Studies also suggest that such associations may vary by dietary fat intake. We investigated associations between the NOS3 Glu298Asp SNP (rs1799983) and hypertension, as well as the...
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