Article
ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans.
PLoS genetics - 16 Sept 2010
Thyagarajan Bargavi, Blaszczak Adam G, Chandler Katherine J, Watts Jennifer L, Johnson W Evan, Graves Barbara J
Abstract excerpt
Aging is a complex phenotype responsive to a plethora of environmental inputs; yet only a limited number of transcriptional regulators are known to influence life span. How the downstream expression programs mediated by these factors (or others) are coordinated into common or distinct set of aging effectors is an addressable question in model organisms, such as C. elegans. Here, we establish the transcription...
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