Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hen1 is required for oocyte development and piRNA stability in zebrafish.

The EMBO journal - 3 Nov 2010

Kamminga Leonie M, Luteijn Maartje J, den Broeder Marjo J, Redl Stefan, Kaaij Lucas J T, Roovers Elke F, Ladurner Peter, Berezikov Eugene, Ketting René F

Abstract excerpt

Piwi-interacting RNAs (piRNAs) are germ line-specific small RNA molecules that have a function in genome defence and germ cell development. They associate with a specific class of Argonaute proteins, named Piwi, and function through an RNA interference-like mechanism. piRNAs carry a 2'-O-methyl modification at their 3' end, which is added by the Hen1 enzyme. We show that zebrafish hen1 is specifically expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryo, Nonmammalian
Share to Immunoprecipitation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methyltransferases

Share to Retroelements

Share to Subcellular Fractions

Share to Testis

Share to Uridine

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20859253
DOI: 10.1038/emboj.2010.233
PMCID: PMC2982757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hen1 is required for oocyte development and piRNA stability in zebrafish.PMID 20859253Read ↗

piRNAs and their involvement in male germline development in mice.Semantic proximity Read ↗

piRNA pathway and the potential processing site, the nuage, in the Drosophila germline.Semantic proximity Read ↗

Gender-Specific Hierarchy in Nuage Localization of PIWI-Interacting RNA Factors in DrosophilaSemantic proximity Read ↗

Zili is required for germ cell differentiation and meiosis in zebrafish.Semantic proximity Read ↗

PIWIL3-piRNA Pathway Is Essential for Rabbit Oogenesis and Embryogenesis via Broad Regulation of the Transcriptome and ProteomeSemantic proximity Read ↗

Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines.Semantic proximity Read ↗

The nuage mediates retrotransposon silencing in mouse primordial ovarian follicles.Semantic proximity Read ↗

piRNA pathway is essential for generating functional oocytes in golden hamsterSemantic proximity Read ↗

PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans.Semantic proximity Read ↗

The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila.Semantic proximity Read ↗

Conserved small nucleotidic elements at the origin of concerted piRNA biogenesis from genes and lncRNAsSemantic proximity Read ↗

Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.