Article
Gender-Specific Hierarchy in Nuage Localization of PIWI-Interacting RNA Factors in Drosophila
1 Jan 2011
Abstract excerpt
PIWI-interacting RNAs (piRNAs) are germline-specific small non-coding RNAs that form piRNA-induced silencing complexes (piRISCs) by associating with PIWI proteins, a subclade of the Argonaute proteins predominantly expressed in the germline. piRISCs protect the integrity of the germline genome from invasive transposable DNA elements by silencing them. Multiple piRNA biogenesis factors have been identified in...
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