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Article

Transforming growth factor-beta modulates proliferation and differentiation of mouse clonal osteoblastic MC3T3-E1 cells depending on their maturation stages.

Bone and mineral - 1 Dec 1990

Katagiri T, Lee T, Takeshima H, Suda T, Tanaka H, Omura S

Abstract excerpt

The effect of transforming growth factor-beta (TGF-beta) on proliferation and differentiation of mouse clonal osteoblastic cells (MC3T3-E1) was examined in vitro in three different stages of their differentiation. Stage I (1-3 days after plating) was characterized by rapid cell growth, negligible...

Topics

Alkaline Phosphatase
Animals
Cell Differentiation
Cell Division
Clone Cells
Collagen
DNA
Mice
Osteoblasts
Phenotype
Proteoglycans
Transforming Growth Factor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2085682
DOI: 10.1016/0169-6009(90)90025-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2085682-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Transforming growth factor-beta modulates proliferation and differentiation of mouse clonal osteoblastic MC3T3-E1 cells depending on their maturation stages.PMID 2085682Read ↗

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