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Article

Role of serum in the developmental expression of alkaline phosphatase in MC3T3-E1 osteoblasts.

Journal of cellular physiology - 1 Mar 1994

Yohay D A, Zhang J, Thrailkill K M, Arthur J M, Quarles L D

Abstract excerpt

MC3T3-E1 cells in culture exhibit a temporal sequence of development similar to in vivo bone formation. To examine whether the developmental expression of the osteoblast phenotype depends on serum derived factors, we compared the time-dependent expression of alkaline phosphatase (ALP)-a marker of osteoblastic maturation- in MC3T3-E1 cells grown in the presence of fetal bovine serum (FBS) or...

Topics

Alkaline Phosphatase
Animals
Blotting, Northern
Cell Differentiation
Cell Line
Charcoal
Colforsin
Mice
Osteoblasts
Phenotype
Resins, Plant
Serum Albumin, Bovine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Time Factors

Up-Regulation

Source

Identifiers

PMID: 8126070
DOI: 10.1002/jcp.1041580311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8126070-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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