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Article

Role of serum in the developmental expression of alkaline phosphatase in MC3T3-E1 osteoblasts.

Journal of cellular physiology - 1 Mar 1994

Yohay D A, Zhang J, Thrailkill K M, Arthur J M, Quarles L D

Abstract excerpt

MC3T3-E1 cells in culture exhibit a temporal sequence of development similar to in vivo bone formation. To examine whether the developmental expression of the osteoblast phenotype depends on serum derived factors, we compared the time-dependent expression of alkaline phosphatase (ALP)-a marker of osteoblastic maturation- in MC3T3-E1 cells grown in the presence of fetal bovine serum (FBS) or...

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PMID: 8126070
DOI: 10.1002/jcp.1041580311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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