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Article

Abnormal differentiation in MC3T3-E1 preosteoblasts expressing a dominant-negative type I collagen mutation.

Connective tissue research - 1 Jan 1996

Wenstrup R J, Witte D P, Florer J B

Abstract excerpt

To examine the effects that an organizing extracellular matrix might have on osteoblast precursors, we created MC3T3-E1 cell lines that stably incorporated a plasmid that expressed pro alpha 1 (I) collagen chains having a truncated triple helical domain. Cells that had incorporated the pro alpha 1 (I) expression plasmid (pMG155) efficiently secreted molecules with shortened pro alpha 1 (I) chains into culture...

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Identifiers

PMID: 9084663
DOI: 10.3109/03008209609029198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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