Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells.

doi:10.1002/jbmr.5650070216

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Article

Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 1992

Franceschi R T, Iyer B S

Abstract excerpt

The MC3T3-E1 mouse calvaria-derived cell line has been used to study the role of collagen synthesis in osteoblast differentiation. MC3T3-E1 cells, like several previously characterized osteoblast culture systems, expressed osteoblast markers and formed a mineralized extracellular matrix only afte...

Topics

Alkaline Phosphatase
Animals
Ascorbic Acid
Biomarkers
Cell Differentiation
Cell Line
Collagen
Extracellular Matrix
Mice
Microscopy, Electron
Minerals
Osteoblasts
Phenotype
RNA
RNA, Messenger
X-Ray Diffraction

Source

Open in PubMed

Identifiers

PMID: 1373931
DOI: 10.1002/jbmr.5650070216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1373931-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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