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Article

Genotyping three SNPs affecting warfarin drug response by isothermal real-time HDA assays.

Clinica chimica acta; international journal of clinical chemistry - 14 Jan 2011

Li Ying, Jortani Saeed A, Ramey-Hartung Bronwyn, Hudson Elizabeth, Lemieux Bertrand, Kong Huimin

Abstract excerpt

BACKGROUND: The response to the anticoagulant drug warfarin is greatly affected by genetic polymorphisms in the VKORC1 and CYP2C9 genes. Genotyping these polymorphisms has been shown to be important in reducing the time of the trial and error process for finding the maintenance dose of warfarin thus reducing the risk of adverse effects of the drug. METHOD: We developed a real-time isothermal DNA amplification...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20854800
DOI: 10.1016/j.cca.2010.09.014
PMCID: PMC2991486

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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