Article
Comparison of assay systems for warfarin-related CYP2C9 and VKORC1 genotyping.
Clinica chimica acta; international journal of clinical chemistry - 4 Jul 2010
Maurice Carleta B, Barua Pankaj K, Simses Diane, Smith Penny, Howe John G, Stack Gary
Abstract excerpt
BACKGROUND: A variety of commercial genotyping assays is available to detect variants in the CYP2C9 and VKORC1 genes. The assay results are used in genotype-based warfarin dosing algorithms. We compared the performance of four such assay systems: Verigene, eSensor, Invader, and Luminex. METHODS: Result concordance and no call rates were determined on patient specimens tested on all four instruments. Turnaround...
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