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Article

Detection of DNA mutations by fluorescence resonance energy transfer-based preferential homoduplex formation assay.

Analytical biochemistry - 15 Jan 2011

Kitano Shiro, Nakayama Mashimo, Yamane Akio, Tsukahara Yusuke, Amano Masahiko

Abstract excerpt

Molecularly targeted agents for cancer therapy are recognized as being effective and are gaining in popularity. However, the efficacy of the agents depends on the status of the targeted molecule such as the number of molecules expressed, activity, and mutation. Therefore, the use of companion diagnostics for investigating the status of the targeted molecule prior to therapy is highly important. We developed a...

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Identifiers

PMID: 20850410
DOI: 10.1016/j.ab.2010.09.012

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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