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Ultrahigh sensitive and selective detection of single nucleotide polymorphism using peptide nucleic acid and ribonuclease H assembled DNA amplification (PRADA).

Analytica chimica acta - 15 Nov 2022

You Juneseok, Jang Kuewhan, Park Hyunjun, Lee Seonwoo, Lim Ahreum, Park Chanho, Park Kyonghwa, Na Sungsoo

Abstract excerpt

Early diagnosis and monitoring of cancer is the best way to increase the survival rate among patients with cancer. However, the current cancer screening technology is expensive and time-consuming; hence, cancer screening remains challenging. Therefore, developing a relatively inexpensive and high-performance analytical method is necessary. Especially, mutations in KRAS can be characterized as single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36283792
DOI: 10.1016/j.aca.2022.340423

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