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Article

Structure of Escherichia coli AlkA in complex with undamaged DNA.

The Journal of biological chemistry - 12 Nov 2010

Bowman Brian R, Lee Seongmin, Wang Shuyu, Verdine Gregory L

Abstract excerpt

Because DNA damage is so rare, DNA glycosylases interact for the most part with undamaged DNA. Whereas the structural basis for recognition of DNA lesions by glycosylases has been studied extensively, less is known about the nature of the interaction between these proteins and undamaged DNA. Here we report the crystal structures of the DNA glycosylase AlkA in complex with undamaged DNA. The structures revealed a...

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Identifiers

PMID: 20843803
DOI: 10.1074/jbc.M110.155663
PMCID: PMC2975202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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