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Article

A new protein architecture for processing alkylation damaged DNA: the crystal structure of DNA glycosylase AlkD.

Journal of molecular biology - 1 Aug 2008

Rubinson Emily H, Metz Audrey H, O'Quin Jami, Eichman Brandt F

Abstract excerpt

DNA glycosylases safeguard the genome by locating and excising chemically modified bases from DNA. AlkD is a recently discovered bacterial DNA glycosylase that removes positively charged methylpurines from DNA, and was predicted to adopt a protein fold distinct from from those of other DNA repair proteins. The crystal structure of Bacillus cereus AlkD presented here shows that the protein is composed exclusively...

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Share to Alkylation
Share to Bacillus cereus
Share to Crystallography, X-Ray

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Damage

Share to DNA Glycosylases

Share to Protein Structure, Tertiary

Share to Sequence Alignment

Share to Structural Homology, Protein

Source

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Identifiers

PMID: 18585735
DOI: 10.1016/j.jmb.2008.05.078
PMCID: PMC3763988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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