Article
Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa.
Journal of neurovirology - 1 Oct 2010
Joska John A, Combrinck Marc, Valcour Victor G, Hoare Jacqueline, Leisegang Felicity, Mahne Anna Cecilia, Myer Landon, Stein Dan J
Abstract excerpt
It is not known whether the apolipoprotein E (ApoE) ε4 allelic variant is associated with human immunodeficiency virus (HIV)-associated dementia (HAD) in a South African population, where HIV clade C is predominant. ApoE genotyping was performed on 144 participants in a larger study of HIV-associated neurocognitive disorders (HAND). There was a lower frequency of the ε2 and ε3 alleles in the...
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