Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulation of sphingolipid and sterol metabolism by ApoE4 in HIV dementia.

Neurology - 24 Aug 2004

Cutler R G, Haughey N J, Tammara A, McArthur J C, Nath A, Reid R, Vargas D L, Pardo C A, Mattson M P

Abstract excerpt

BACKGROUND: Polymorphisms in apolipoprotein E have been associated with worse prognoses in numerous neurodegenerative conditions, including HIV dementia (HIVD). Despite these correlative observations, there has been little evidence suggesting a mechanism whereby the expression of ApoE4 renders ne...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS Dementia Complex
Share to Brain Chemistry
Share to Ceramides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipid Peroxidation

Share to Membrane Lipids

Share to Phospholipids

Share to Sphingolipids

Share to Sterols

Source

Identifiers

PMID: 15326233
DOI: 10.1212/01.wnl.0000134662.19883.06

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15326233-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulation of sphingolipid and sterol metabolism by ApoE4 in HIV dementia.PMID 15326233Read ↗

HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy.Semantic proximity Read ↗

Genomic Factors and Therapeutic Approaches in HIV-Associated Neurocognitive Disorders: A Comprehensive ReviewSemantic proximity Read ↗

Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers.Semantic proximity Read ↗

Apolipoprotein E genotype and hepatitis C, HIV and herpes simplex disease risk: a literature review.Semantic proximity Read ↗

Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression.Semantic proximity Read ↗

APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals - a cross-sectional observational study.Semantic proximity Read ↗

HIV-Associated Neurocognitive Disorder (HAND) and Alzheimer’s Disease Pathogenesis: Future Directions for Diagnosis and TreatmentSemantic proximity Read ↗

Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy.Semantic proximity Read ↗

Correlation of APOE polymorphism, expression, and plasma levels with cardiac comorbidities among lipodystrophy in HIV-infected patients.Semantic proximity Read ↗

APOE ε 4 allele and CSF APOE on cognition in HIV-infected subjects.Semantic proximity Read ↗

Apolipoprotein E4 genotype does not increase risk of HIV-associated neurocognitive disorders.Semantic proximity Read ↗

ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.