Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship between apolipoprotein E4 genotype and white matter integrity in HIV-positive young adults in South Africa.

European archives of psychiatry and clinical neuroscience - 1 Apr 2013

Hoare Jacqueline, Westgarth-Taylor Jenny, Fouche Jean-Paul, Combrinck Marc, Spottiswoode Bruce, Stein Dan J, Joska John A

Abstract excerpt

HIV-associated dementia (HAD) is a serious neuropsychiatric disorder affecting people with AIDS. Host genotype may affect the pathogenesis of HIV in the central nervous system (CNS). One gene relevant to the individual variation in acquiring HAD may be Apolipoprotein E (ApoE). We aimed to investigate the relationship of ApoE genotype to neuropsychological function and white matter integrity of the corpus callosum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS Dementia Complex
Share to CD4 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Corpus Callosum

Share to Diffusion Tensor Imaging

Share to Nerve Fibers, Myelinated

Share to Psychiatric Status Rating Scales

Share to South Africa

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 22825739
DOI: 10.1007/s00406-012-0341-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between apolipoprotein E4 genotype and white matter integrity in HIV-positive young adults in South Africa.PMID 22825739Read ↗

ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60.Semantic proximity Read ↗

Apolipoprotein E ε4 genotype status is not associated with neuroimaging outcomes in a large cohort of HIV+ individuals.Semantic proximity Read ↗

Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severitySemantic proximity Read ↗

APOE ε 4 allele and CSF APOE on cognition in HIV-infected subjects.Semantic proximity Read ↗

Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa.Semantic proximity Read ↗

White-Matter Damage in Clade C HIV-Positive Subjects: A Diffusion Tensor Imaging StudySemantic proximity Read ↗

White-Matter Damage in Clade C HIV-Positive Subjects: A Diffusion Tensor Imaging StudySemantic proximity Read ↗

Association of apolipoprotein E epsilon 4 and cognitive impairment in adults living with human immunodeficiency virus: a meta-analysis.Semantic proximity Read ↗

APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals - a cross-sectional observational study.Semantic proximity Read ↗

Dysregulation of sphingolipid and sterol metabolism by ApoE4 in HIV dementia.Semantic proximity Read ↗

Single nucleotide polymorphisms in aquaporin-4 associate with cognitive impairment status in people with HIV.Semantic proximity Read ↗

Apolipoprotein E4 genotype does not increase risk of HIV-associated neurocognitive disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.