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Article

APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donors.

AIDS (London, England) - 19 Jun 2010

Spector Stephen A, Singh Kumud K, Gupta Saurabh, Cystique Lucette A, Jin Hua, Letendre Scott, Schrier Rachel, Wu Zunyou, Hong Kun X, Yu Xin, Shi Chuan, Heaton Robert K

Abstract excerpt

BACKGROUND: Host genetic factors are important determinants for risk of HIV-1 infection and disease progression. This study examined associations of host genetic variants and neurocognitive impairment in Chinese individuals infected through contaminated blood products. METHODS: Two hundred and one HIV-infected patients from Anhui, China, had neuropsychological tests at baseline and 12 months. DNA was genotyped...

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Source

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Identifiers

PMID: 20442634
DOI: 10.1097/QAD.0b013e328339e25c
PMCID: PMC3063510

Genes

APOE
MBL2
CCR5
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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