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Article

ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60.

Journal of acquired immune deficiency syndromes (1999) - 1 Dec 2016

Wendelken Lauren A, Jahanshad Neda, Rosen Howard J, Busovaca Edgar, Allen Isabel, Coppola Giovanni, Adams Collin, Rankin Katherine P, Milanini Benedetta, Clifford Katherine, Wojta Kevin, Nir Talia M, Gutman Boris A, Thompson Paul M, Valcour Victor

Abstract excerpt

BACKGROUND: There are contradicting reports on the associations between Apolipoprotein E4 (ApoE ε4) and brain outcomes in HIV with some evidence that relationships may be greatest in older age groups. METHODS: We assessed cognition in 76 clinically stable HIV-infected participants over age 60 and genotyped ApoE. Sixty-one of these subjects underwent structural brain magnetic resonance imaging and diffusion tensor...

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Identifiers

PMID: 27228100
DOI: 10.1097/QAI.0000000000001091
PMCID: PMC5085854

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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