Article
Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii Aging with HIV Cohort.
Journal of neuroimmunology - 1 Dec 2004
Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes O A, Grove J, Liu Y, Abdul-Majid K-B, Gartner S, Sacktor N
Abstract excerpt
There are discrepant findings regarding the risk of HIV-associated dementia (HAD) relating to apolipoprotein E4, suggesting other factors may modulate risk. Furthermore, evidence suggests a changing phenotype of HAD in the era of highly active antiretroviral therapy (HAART), prompting a need to determine if new disease markers have emerged. In this analysis, APOE genotype was determined for 182 participants...
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