Article
The mitogen-activated protein kinase Slt2 regulates nuclear retention of non-heat shock mRNAs during heat shock-induced stress.
Molecular and cellular biology - 1 Nov 2010
Carmody Sean R, Tran Elizabeth J, Apponi Luciano H, Corbett Anita H, Wente Susan R
Abstract excerpt
Cellular adaptation to environmental stress conditions requires rapid and specific changes in gene expression. During heat shock, most polyadenylated mRNAs are retained in the nucleus, whereas the export of heat shock-induced mRNAs is allowed. Although essential mRNA export factors are known, the precise mechanism for regulating transport is not fully understood. Here we find that during heat shock in...
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