Article
Distinct modes of stress granule assembly mediated by the KH-type RNA-binding protein Rnc1.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2018
Satoh Ryosuke, Hara Nobuki, Kawasaki Aki, Takasaki Teruaki, Sugiura Reiko
Abstract excerpt
We have previously identified the KH-type RNA-binding protein Rnc1 as an important regulator of the posttranscriptional expression of the MAPK phosphatase Pmp1 in fission yeast. Rnc1 localization in response to stress has not been elucidated thus far. Here, we report the dual roles of Rnc1 in assembly of stress granules (SGs), nonmembranous cytoplasmic foci composed of messenger ribonucleoproteins. Rnc1 can...
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