Article
Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts.
The Journal of biological chemistry - 24 Mar 2000
Hurt E, Strässer K, Segref A, Bailer S, Schlaich N, Presutti C, Tollervey D, Jansen R
Abstract excerpt
Mex67p is essential for nuclear poly(A)(+) RNA export in yeast, but which specific transcripts are transported by Mex67p is not known. We observed that thermosensitive mex67-5 cells do not produce a heat shock response at 37 degrees C but will induce heat shock proteins (Hsp) (e.g. Hsp104p and Hsp70p) when shifted back from the restrictive to permissive temperature (30 degrees C). This memory of a previous heat...
Topics
- Adenosine Triphosphatases
- Biological Transport
- Cell Nucleus
- DNA-Binding Proteins
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Heat-Shock Response
- Membrane Proteins
- Mutation
- Nuclear Pore Complex Proteins
- Nuclear Proteins
- Nucleocytoplasmic Transport Proteins
- Phosphoglycerate Kinase