Article
You can win by losing: p53 mutations in rhabdomyosarcomas.
The Journal of pathology - 1 Oct 2010
Post Sean M, Lozano Guillermina
Abstract excerpt
Rhabdomyosarcomas are soft tissue sarcomas of mesenchymal origin. Unlike rhabdomyosarcomas observed in paediatric patients which typically respond well to chemotherapeutic treatment, adults generally present with pleomorphic rhabdomyosarcomas that are typically associated with poor prognosis. Therefore, understanding the molecular biology that gives rise to pleomorphic rhabdomyosarcomas is critical. In this issue...
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