Developmental origins of fusion-negative rhabdomyosarcomas.

Abstract excerpt

Rhabdomyosarcomas (RMS) are very heterogeneous tumors that can be divided into three major groups: alveolar rhabdomyosarcoma, embryonal rhabdomyosarcoma, and pleomorphic rhabdomyosarcoma. Concerted efforts over the past a decade have led to an understanding of the genetic underpinnings of many human tumors through genetically engineered models; however, left largely behind in this effort have been rare tumors...

Topics

• Animals
• Cell Transformation, Neoplastic
• Humans
• Neoplastic Stem Cells
• Phenotype
• Rhabdomyosarcoma