Article
Advances in pediatric rhabdomyosarcoma characterization and disease model development.
Histology and histopathology - 1 Jan 2012
O'Brien D, Jacob A G, Qualman S J, Chandler D S
Abstract excerpt
Rhabdomyosarcoma (RMS), a form of soft tissue sarcoma, is one of the most common pediatric malignancies. A complex disease with at least three different subtypes, it is characterized by perturbations in a number of signaling pathways and genetic abnormalities. Extensive clinical studies have helped classify these tumors into high and low risk groups to facilitate different treatment regimens. Research into the...
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