Article
Site analysis of recombinant and mutant poliovirus isolates of Sabin origin from patients and from vaccinees.
Molecular and cellular probes - 1 Apr 2004
Karakasiliotis Ioannis, Markoulatos Panayotis, Katsorchis Theodoros
Abstract excerpt
Recombination in vaccine strains of polioviruses is a very frequent phenomenon. In the present report, 12 strains isolated from patients after OPV administration and healthy vaccinees were investigated for the identification of recombinant strains as well as for the further analysis of their recombination types and the localization of the recombination sites. The identification of these strains was achieved...
Topics
- Base Sequence
- Humans
- Molecular Sequence Data
- Mutation
- Poliomyelitis
- Poliovirus
- Poliovirus Vaccine, Oral
- Polymorphism, Restriction Fragment Length
- RNA, Viral
- Recombination, Genetic
- Reverse Transcriptase Polymerase Chain Reaction