Article
Molecular and Phenotypic Characterization of a Highly Evolved Type 2 Vaccine-Derived Poliovirus Isolated from Seawater in Brazil, 2014.
PloS one - 1 Jan 2016
Cassemiro Klécia Marília S de Melo, Burlandy Fernanda M, Barbosa Mikaela R F, Chen Qi, Jorba Jaume, Hachich Elayse M, Sato Maria I Z, Burns Cara C, da Silva Edson E
Abstract excerpt
A type 2 vaccine-derived poliovirus (VDPV), differing from the Sabin 2 strain at 8.6% (78/903) of VP1 nucleotide positions, was isolated from seawater collected from a seaport in São Paulo State, Brazil. The P1/capsid region is related to the Sabin 2 strain, but sequences within the 5'-untranslat...
Topics
- 5' Untranslated Regions
- Amino Acid Sequence
- Amino Acid Substitution
- Antibodies, Viral
- Brazil
- Capsid Proteins
- Cell Line
- Humans
- Molecular Sequence Data
- Phenotype
- Phylogeny
- Poliovirus
- Promoter Regions, Genetic
- Real-Time Polymerase Chain Reaction