Article
Population pharmacokinetics and Bayesian estimation of tacrolimus exposure in renal transplant recipients on a new once-daily formulation.
Clinical pharmacokinetics - 1 Oct 2010
Benkali Khaled, Rostaing Lionel, Premaud Aurélie, Woillard Jean-Baptiste, Saint-Marcoux Franck, Urien Saik, Kamar Nassim, Marquet Pierre, Rousseau Annick
Abstract excerpt
BACKGROUND AND OBJECTIVES: Advagraf is a new extended-release once-daily formulation of tacrolimus, a potent immunosuppressant widely used in renal transplantation. The aims of his study were (i) to develop a population pharmacokinetic model for once-daily tacrolimus in adult renal transplant pat...
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