Article
Population pharmacokinetic model and Bayesian estimator for two tacrolimus formulations--twice daily Prograf and once daily Advagraf.
British journal of clinical pharmacology - 1 Mar 2011
Woillard Jean-Baptiste, de Winter Brenda C M, Kamar Nassim, Marquet Pierre, Rostaing Lionel, Rousseau Annick
Abstract excerpt
AIM: To investigate the differences in the pharmacokinetics of Prograf and the prolonged release formulation Advagraf and to develop a Bayesian estimator to estimate tacrolimus inter-dose area under the curve (AUC) in renal transplant patients receiving either Prograf or Advagraf. METHODS: Tacrol...
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