Article
Cloning and expression of surface antigens from occult chronic hepatitis B virus infections and their recognition by commercial detection assays.
Journal of medical virology - 1 Aug 2004
Jeantet Damien, Chemin Isabelle, Mandrand Bernard, Tran Albert, Zoulim Fabien, Merle Philippe, Trepo Christian, Kay Alan
Abstract excerpt
Occult hepatitis B virus (HBV) infections show little or no serological markers of viral infection, including the absence of hepatitis B surface antigen (HBsAg) which is the main marker of ongoing HBV infection. Such infections can be important in the context of blood and/or organ donations. To study whether mutations contribute to HBsAg seronegativity, S gene sequences from such patients were amplified and...
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