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Article

Occult hepatitis B virus infection: influence of S protein variants.

Virology journal - 19 Jan 2016

Zhang Zhenhua, Zhang Ling, Dai Yu, Zhang Yafei, Li Jun, Li Xu

Abstract excerpt

BACKGROUND: In occult hepatitis B viral infection (OBI), the persistence of hepatitis B virus (HBV) DNA is associated with a lack of hepatitis B surface antigen (HBsAg). To assess the possible role of HBsAg immune escape variants in OBI patients, variability in the HBV S gene was evaluated for OBI patients as well as chronic HBV infection patients from the same families. METHODS: We selected 17 HBV...

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Identifiers

PMID: 26786229
DOI: 10.1186/s12985-016-0464-z
PMCID: PMC4717550

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